Investigation of migrants from can coatings: Occurrence in canned foodstuffs and exposure assessment

Abstract

In the present study migrants from can coatings, specifically epoxy and polyester resins, were determined in canned foods. Targeted and non-targeted approaches were applied to explore the migrating compounds. Bisphenol A (BPA), BADGE .2 H2O, BADGE·H2O.HCl and cyclodiBADGE from epoxy resins and three monomers i.e., terephthalic acid (TPA), phthalic acid (PA), isophthalic acid (IPA) and four tentatively identified oligomers from polyester resins were found in the foodstuffs. Using the consumption data from the Spanish consumption survey, dietary exposure to these chemicals was assessed. Mainly, our data suggested low exposure to the migrants evaluated, however, it is important to highlight that cyclic oligomers showed the highest mean exposure (0.00646–2.75 μg/kg bw/day) and these molecules belong to Cramer class III, which means that they may have significant toxicity.