Lipidic lyotropic liquid crystals: insights on biomedical applications

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dc.contributor.affiliationUniversidade de Santiago de Compostela. Departamento de Farmacoloxía, Farmacia e Tecnoloxía Farmacéuticagl
dc.contributor.authorBlanco Fernández, Guillermo
dc.contributor.authorBlanco Fernandez, Bárbara
dc.contributor.authorFernández Ferreiro, Anxo
dc.contributor.authorOtero Espinar, Francisco Javier
dc.date.accessioned2023-05-26T06:38:43Z
dc.date.available2023-05-26T06:38:43Z
dc.date.issued2023
dc.description.abstractLiquid crystals (LCs) possess unique physicochemical properties, translatable into a wide range of applications. To date, lipidic lyotropic LCs (LLCs) have been extensively explored in drug delivery and imaging owing to the capability to encapsulate and release payloads with different characteristics. The current landscape of lipidic LLCs in biomedical applications is provided in this review. Initially, the main properties, types, methods of fabrication and applications of LCs are showcased. Then, a comprehensive discussion of the main biomedical applications of lipidic LLCs accordingly to the application (drug and biomacromolecule delivery, tissue engineering and molecular imaging) and route of administration is examined. Further discussion of the main limitations and perspectives of lipidic LLCs in biomedical applications are also providedgl
dc.description.peerreviewedSIgl
dc.description.sponsorshipThis research was supported by the Spanish Ministry of Science, Innovation and Universities (RTI2018-099597-B-100). Instituto de Salud Carlos III (ISCIII)/ (PI20/00719, cofounded by European Union and JR18/00014) and by Xunta de Galicia (ED431C2021/26, IN607D2021/01)gl
dc.identifier.citationAdvances in Colloid and Interface Science 313 (2023) 102867gl
dc.identifier.doi10.1016/j.cis.2023.102867
dc.identifier.essn0001-8686
dc.identifier.urihttp://hdl.handle.net/10347/30607
dc.language.isoenggl
dc.publisherElseviergl
dc.relation.projectIDinfo:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2017-2020/RTI2018-099597-B-100gl
dc.relation.publisherversionhttps://doi.org/10.1016/j.cis.2023.102867gl
dc.rights© 2023 The Authors. Published by Elsevier B.V. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/)
dc.rights.accessRightsopen accessgl
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.subjectLiquid crystalsgl
dc.subjectDrug deliverygl
dc.subjectImaginggl
dc.subjectTissue engineeringgl
dc.subjectGlycerol monooleategl
dc.titleLipidic lyotropic liquid crystals: insights on biomedical applicationsgl
dc.typejournal articlegl
dc.type.hasVersionVoRgl
dspace.entity.typePublication
relation.isAuthorOfPublicatione1eb8f2f-9516-4a0f-8819-2cad31053b62
relation.isAuthorOfPublication.latestForDiscoverye1eb8f2f-9516-4a0f-8819-2cad31053b62

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