Food intake regulating-neuropeptides are expressed and regulated through pregnancy and following food restriction in rat placenta

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dc.contributor.affiliationUniversidade de Santiago de Compostela. Departamento de Fisioloxíagl
dc.contributor.authorCaminos, Jorge E.
dc.contributor.authorBravo López, Susana Belén
dc.contributor.authorGonzález Dieguez, Carmen Ruth
dc.contributor.authorGarcés, Maria F.
dc.contributor.authorCepeda, Libia A.
dc.contributor.authorGonzález, Adriana C.
dc.contributor.authorCodido, Fernando
dc.contributor.authorLópez Pérez, Miguel A.
dc.contributor.authorDiéguez González, Carlos
dc.date.accessioned2020-06-06T18:50:33Z
dc.date.available2020-06-06T18:50:33Z
dc.date.issued2008
dc.description.abstractBackground Neuropeptide Y (NPY), agouti related peptide (AgRP), cocaine and amphetamine-regulated transcript (CART) and melanocortins, the products of the proopiomelanocortin (POMC), are hypothalamic peptides involved in feeding regulation and energy homeostasis. Recent evidence has demonstrated their expression in rat and human placenta. Methods In the current study, we have investigated the expression of those neuropeptides in the rat placenta by real-time PCR using a model of maternal food restriction. Results Our results showed that placental-derived neuropeptides were regulated through pregnancy and following food restriction. Conclusion These data could indicate that placental-derived neuropeptides represent a local regulatory circuit that may fine-tune control of energy balance during pregnancygl
dc.description.peerreviewedSIgl
dc.description.sponsorshipThis work has been supported by grants from Xunta de Galicia (ML: GRC2006/66), Fondo Investigationes Sanitarias (ML: PI061700), Ministerio de Educacion y Ciencia (CD: BFU2005), Mútua Madrileña (CD and ML) and European Union (CD: LSHM-CT-2003-503041)gl
dc.identifier.citationCaminos, J.E., Bravo, S.B., González, C.R. et al. Food intake regulating-neuropeptides are expressed and regulated through pregnancy and following food restriction in rat placenta. Reprod Biol Endocrinol 6, 14 (2008)gl
dc.identifier.doi10.1186/1477-7827-6-14
dc.identifier.issn1477-7827
dc.identifier.urihttp://hdl.handle.net/10347/22884
dc.language.isoenggl
dc.publisherBMCgl
dc.relation.publisherversionhttps://doi.org/10.1186/1477-7827-6-14gl
dc.rights© 2008 Caminos et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly citedgl
dc.rights.accessRightsopen accessgl
dc.rights.urihttp://creativecommons.org/licenses/by/2.0
dc.subjectReverse Transcription Polymerase Chain Reactiongl
dc.subjectFood Restrictiongl
dc.subjectPOMC Expressiongl
dc.subjectChronic Food Restrictiongl
dc.subjectAgouti Related Peptidegl
dc.titleFood intake regulating-neuropeptides are expressed and regulated through pregnancy and following food restriction in rat placentagl
dc.typejournal articlegl
dc.type.hasVersionVoRgl
dspace.entity.typePublication
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relation.isAuthorOfPublication5e85852a-86da-4c51-a990-34cc008a3ae7
relation.isAuthorOfPublication.latestForDiscovery5e85852a-86da-4c51-a990-34cc008a3ae7

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