Therapeutic alternatives research for the treatment of ocular inflammatory diseases

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dc.contributor.advisorOtero Espinar, Francisco Javier
dc.contributor.advisorFernández Ferreiro, Anxo
dc.contributor.advisorAguiar Fernández, Pablo
dc.contributor.affiliationUniversidade de Santiago de Compostela. Escola de Doutoramento Internacional (EDIUS)
dc.contributor.authorGarcía Otero, Xurxo
dc.date.accessioned2023-01-18T08:10:38Z
dc.date.available2023-01-18T08:10:38Z
dc.date.issued2022
dc.description.abstractIn the present thesis, different formulations of tacrolimus for topical-ophthalmic administration have been proposed, supported by extensive preclinical studies in order to achieve a consistent basis for the treatment of ocular inflammatory diseases. On the other hand, a pharmacokinetic and distribution study of an anti-TNFα monoclonal antibody (adalimumab) injected intravitreally was also carried out, allowing to know its behavior in the eye and thus develop new administration systems.gl
dc.description.programaUniversidade de Santiago de Compostela. Programa de Doutoramento en Investigación e Desenvolvemento de Medicamentos
dc.identifier.urihttp://hdl.handle.net/10347/29914
dc.language.isoenggl
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 Internacional
dc.rights.accessRightsopen accessgl
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subjectocular inflammatory diseasesgl
dc.subjecttacrolimusgl
dc.subjectadalimumabgl
dc.subjectpharmacokineticsgl
dc.subjectdrug deliverygl
dc.subject.classificationMaterias::Investigación::32 Ciencias médicas::3209 Farmacología::320901 Análisis de medicamentosgl
dc.subject.classificationMaterias::Investigación::32 Ciencias médicas::3208 Farmacodinámica::320801 Absorción de medicamentosgl
dc.subject.classificationMaterias::Investigación::32 Ciencias médicas::3209 Farmacología::320990 Farmacología experimentalgl
dc.titleTherapeutic alternatives research for the treatment of ocular inflammatory diseasesgl
dc.typedoctoral thesisgl
dspace.entity.typePublication
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