A Generalized Model to Estimate the Statistical Power in Mitochondrial Disease Studies Involving 2×k Tables

Thumbnail Image

Files

2013_pone_pardo_generalized.PDF (901.32 KB)
Identifiers
URI: http://hdl.handle.net/10347/18534
E-ISSN: 1932-6203
DOI: 10.1371/journal.pone.0073567

Publication date

2013

Authors

Advisors

Tutors

Editors

Journal Title

Journal ISSN

Volume Title

Publisher

Public Library of Science
Metrics
Google Scholar
lacobus
Export

Research Projects

Organizational Units

Journal Issue

Abstract

Mitochondrial DNA (mtDNA) variation (i.e. haplogroups) has been analyzed in regards to a number of multifactorial diseases. The statistical power of a case-control study determines the a priori probability to reject the null hypothesis of homogeneity between cases and controls

Description

Keywords

Haplogroups| Mitochondrial DNA| Permutation| Case-control studies| Contingency tables| Statistical distributions| Haplotypes| Web-based applications

Bibliographic citation

Pardo-Seco J, Amigo J, González-Manteiga W, Salas A (2013) A Generalized Model to Estimate the Statistical Power in Mitochondrial Disease Studies Involving 2×k Tables. PLoS ONE 8(9): e73567. https://doi.org/10.1371/journal.pone.0073567

Relation

Has part

Has version

Is based on

Is part of

Is referenced by

Is version of

Requires

Sponsors

The research leading to these results has received funding from the “Ministerio de Ciencia e Innovación” (SAF2008-02971) and from the Plan Galego IDT, Xunta de Galicia (EM 2012/045) given to A.S.

Rights

© 2013 Pardo-Seco et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited
Atribución 4.0 Internacional

Collections

MODESTYA
Ciencias Forenses, Anatomía Patolóxica, Xinecoloxía e Obstetricia e Pediatría
Estatística, Análise Matemática e Optimización