Sequence‐Specific DNA Recognition with Designed Peptides
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Abstract
Inspired by natural transcription factors (TFs), researchers have explored the potential of artificial peptides for the recognition of specific DNA sequences, developing increasingly sophisticated systems that not only display excellent DNA binding properties, but also are endowed with new properties not found in their natural counterparts. Here we review some of the developments in the field of artificial peptide‐based DNA binders, focusing on the supramolecular and molecular design aspects of such systems
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This is the peer reviewed version of the following article: Boga, S., Bouzada, D., García Peña, D., Vázquez López, M. and Vázquez, M. E. (2018), Sequence‐Specific DNA Recognition with Designed Peptides. Eur. J. Org. Chem., 2018: 249-261, which has been published in final form at https://doi.org/10.1002/ejoc.201700988.
This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions
Bibliographic citation
Boga, S., Bouzada, D., García Peña, D., Vázquez López, M. and Vázquez, M. E. (2018), Sequence‐Specific DNA Recognition with Designed Peptides. Eur. J. Org. Chem., 2018: 249-261. doi:10.1002/ejoc.201700988
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https://doi.org/10.1002/ejoc.201700988Sponsors
Secretaría de Estado de Investigación, Desarrollo e Innovación. Grant Number: CTQ2015‐70698‐R
Consellería de Cultura, Educación e Ordenación Universitaria, Xunta de Galicia. Grant Number: ED431G/09
Fundación Científica Asociación Española Contra el Cáncer. Grant Number: IDEAS197VAZQ
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© 2018 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim. This article may be used for non-commercial purposes in accordance with Wiley-VCH Terms and Conditions for Self-Archiving